NPEs (nonylphenol ethoxylates) break down in the environment into nonylphenol (NP), one of the most notorious examples of persistent, bioaccumulative and toxic chemicals (PBTs). Widely recognized for extreme aquatic toxicity to fish and wildlife, NPEs and NP may also threaten the health of the developing fetus and young children.

Nonyl-phenol ethoxylates have much narrower homologue distributions than alcohol ethoxylates (ICI datasheet for Synperonic NP surfactants). 880 million pounds (4 mio metric tonnes) of alkyl phenol ethoxylates are used annually throughout the world. 80-85% are sold as nonylphenol ethoxylate (NPE), over 15% as octylphenol ethoxylate, and 1% each as

According to the classification provided by companies to ECHA in CLP notifications this substance is toxic to aquatic life with long lasting effects, causes serious eye damage, is harmful if swallowed and causes skin irritation. Breakdown of all 4512 C&L notifications submitted to ECHA Intergenerational toxicity of nonylphenol ethoxylate (NP-9) in Caenorhabditis elegans. De la Parra-Guerra A(1), Stürzenbaum S(2), Olivero-Verbel J(3). Author information: (1)Environmental and Computational Chemistry Group, University of Cartagena, Cartagena, Colombia.

Nonylphenol ethoxylate toxicity

Nonylphenol and its ethoxylates. • EC (2001), EU-RAR on 4-nonylphenol (branched) and Nonylphenol. Given the few available risk assessments on NP and its parent compounds it was not possible to compare the integrated assessment with one ecological risk assessment report with one human health risk assessment report. Nonylphenol (NP) (CAS number, 104-40-05) is a product of industrial synthesis formed during the alkylation process of phenols (ring structure in Figure 1). The addition of ethoxyl groups to the parent compound produces nonylphenol ethoxylates (NPE), which are used to produce industrial surfactants. As per the Government of Canada (2007), “Nonylphenol ethoxylates (NPEs) are a class of the broader group of compounds known as alkylphenol ethoxylates (APEs). NPEs are high-volume chemicals that have been used for more than 40 years as detergents, emulsifiers, wetting agents and dispersing agents.

NP’s main use is in the manufacture of NPEs.

2019年10月22日 Among the most used chemicals in the world are nonionic surfactants. One of these environmental pollutants is nonylphenol ethoxylate (NP-9),

Primary biodeg-radation of NPEs in aquatic systems is fast, but the resul-tant products, nonylphenol monoethoxylate (NP1EO), Nonylphenol is highly toxic to aquatic organisms and has been found in natural waters. Because of nonylphenol's toxicity, chemical properties, and widespread use to make other chemicals, concerns have been raised over the potential risks to aquatic organisms from exposure to nonylphenol. of nonylphenol ethoxylates produces more toxic nonylphenol (NP) (Hano et al., 2009).

27 Nov 2016 Nonylphenol Ethoxylates (NPE) are used in a wide variety of industrial applications and consumer products. NPEs, though less toxic than NP,

Since soil and sediment toxicity data were virtually absent, 11 Feb 2014 purpose cleaning products containing nonylphenol ethoxylates. As NPE clearly requires replacement, mainly due to the environmental toxicity 5 Jan 2017 Nonylphenol ethoxylate-6. Shrimp. Penaeus vannamei.

They are used as detergents, emulsifiers, wetting agents, defoaming agents, etc.
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Acute toxicity - oral Reason for no classification: data conclusive but not sufficient for classification Acute toxicity - dermal Reason for no classification: data lacking Acute toxicity - inhalation Reason for no classification: data lacking Skin corrosion / irritation Hazard category: Skin Irrit. 2 Hazard statement: H315: Causes skin irritation. Acute toxicity tests using nonylphenol (NP), nonylphenol monoethoxylate (NP1EO), and nonylphenol diethoxylate (NP2EO) were conducted using the single chemicals and as binary and tertiary mixtures. These compounds frequently coexist in surface waters as the result of discharges from wastewater treatment plants that are inefficient at removing nonylphenolic compounds.

Nonylphenol ethoxylates in imported textiles iii Abstract Nonylphenol is a priority hazardous substance under the Water Framework Directive (WFD) due to its potential impact upon the aquatic environment.
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absence of other nonylphenol ethoxylate (NPE) degradation by-products, the toxicity, fate and behaviour of some of these (i.e. nonylphenol mono- and diethoxylates (NP1EO and NP2EO), mono- and di-nonylphenoxy carboxylic acids (NP1EC and NP2EC) have also been considered in this report.

Acute toxicity (oral), Category 4 H302 Skin corrosion/irritation, Category 1B H314 Reproductive toxicity, Category 2 H361fd Hazardous to the aquatic environment — Chronic Hazard, Category 1 H410 Full text of classification categories and H statements : see section 16 Classification according to Directive 67/548/EEC or 1999/45/EC Repr.Cat.3; R62 Request PDF | Toxicity of nonylphenol and nonylphenol ethoxylate on Caenorhabditis elegans | Among the most used chemicals in the world are nonionic surfactants. One of these environmental Nonylphenol Ethoxylates (NPE) in All-Purpose Cleaners LAE linear alcohol ethoxylate LAS linear alkylbenzene sulfonate LC 50 median lethal concentration LCI Life cycle inventory LD 50 R reproductive toxicity REACH Registration, Evaluation, Authorisation and Restriction of Chemical Substances Currently, the aquatic toxicity testing EPA is considering would focus on testing NP and the short-chain NPEs, i.e., nonylphenol with one or two ethoxylates groups attached. EPA is soliciting comment on the most appropriate selection and purity of NP and NPEs to test.